Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury

Overexpression of Msx1 in Mouse Lung Leads to Loss of Pulmonary Vessels Following Vascular Hypoxic Injury

Pulmonary arterial hypertension (PAH) is a progressive lung disease caused by thickening of the pulmonary arterial wall and luminal obliteration of the small peripheral arteries leading to increase in vascular resistance which elevates pulmonary artery pressure that eventually causes right heart fai...

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Bibliographic Details
Main Authors: James West, Anandharajan Rathinasabapathy, Xinping Chen, Sheila Shay, Shanti Gladson, Megha Talati
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cells
Subjects:
pulmonary arterial hypertension
Msx1 expression
mouse models
pulmonary vascular endothelial cells
pulmonary vascular smooth muscle cells
BMP pathway
Online Access:https://www.mdpi.com/2073-4409/10/9/2306

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