Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility

Galectin-1 and galectin-3 expression in equine mesenchymal stromal cells (MSCs), synovial fibroblasts and chondrocytes, and the effect of inflammation on MSC motility

Abstract Background Mesenchymal stromal cells (MSCs) can be used intra-articularly to quell inflammation and promote cartilage healing; however, mechanisms by which MSCs mitigate joint disease remain poorly understood. Galectins, a family of β-galactoside binding proteins, regulate inflammation, adh...

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Bibliographic Details
Main Authors: Heidi L. Reesink, Ryan M. Sutton, Carolyn R. Shurer, Ryan P. Peterson, Julie S. Tan, Jin Su, Matthew J. Paszek, Alan J. Nixon
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Stem Cell Research & Therapy
Subjects:
Osteoarthritis
Adhesion
Migration
Horse
Stem cell
IL-1β
Online Access:http://link.springer.com/article/10.1186/s13287-017-0691-2

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