Serum free fatty acids levels not associated with normal tension glaucoma

• Main Authors: Kenya Yuki, Itaru Kimura, Kazuo Tsubota
• Format: Article
• Language: English
• Published: Dove Medical Press 2010-02-01
• Series: Clinical Ophthalmology
• Online Access: http://www.dovepress.com/serum-free-fatty-acids-levels-not-associated-with-normal-tension-glauc-a3989

Kenya Yuki, Itaru Kimura, Kazuo TsubotaDepartment of Ophthalmology, Keio University School of Medicine, Tokyo, JapanPurpose: To determine the free fatty acid levels in the sera of patients with normal-tension glaucoma and compare it with that of normal controls.Methods: Forty-four consecutive patients with newly diagnosed normal-tension glaucoma and forty-four age and gender matched controls were evaluated. The type and level of fatty acids in the sera were measured by gas chromatography (Model GC17A; Shimazu, Kyoto, Japan). Twenty-four fatty acids were identified from 12:0 to 24:1. The values were compared between the normal-tension glaucoma and control groups by Mann–Whitney U tests.Results: No statistically significant difference was found in the levels of any free fatty acids between the normal-tension glaucoma group and control group.Conclusion: No significant association was found in the serum free fatty acids levels including docosahexaenoic acid and eicosapentaenoic acid between normal-tension glaucoma patients and controls.Keywords: free fatty acid, docosahexaenoic acid, eicosapentaenoic acid, normal tension glaucoma