Interplay between transcription factors and the epigenome: Insight from the role of RUNX1 in leukemia.

The genome has the ability to respond in a precise and co-ordinated manner to cellular signals. It achieves this through the concerted actions of transcription factors and the chromatin platform, which are targets of the signalling pathways. Our understanding of the molecular mechanisms through whic...

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Bibliographic Details
Main Authors: Kate Helen Brettingham-Moore, Phillippa Claire Taberlay, Adele Frances Holloway
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00499/full

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