Dietary thiols accelerate aging of C. elegans

Dietary thiols accelerate aging of C. elegans

Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress resistance in worms and human cells, and extends C...

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Bibliographic Details
Main Authors: Ivan Gusarov, Ilya Shamovsky, Bibhusita Pani, Laurent Gautier, Svetlana Eremina, Olga Katkova-Zhukotskaya, Alexander Mironov, Alexander А. Makarov, Evgeny Nudler
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24634-3
Description
Summary:Reactive oxygen species are required for the long lifespan, and glutathione is an antioxidant. Here the authors show that limiting the consumption of dietary thiols, including those naturally derived from the microbiota, increases proteotoxic stress resistance in worms and human cells, and extends C. elegans lifespan.
ISSN:2041-1723

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