HDAC6 Degradation Inhibits the Growth of High-Grade Serous Ovarian Cancer Cells

HDAC6 Degradation Inhibits the Growth of High-Grade Serous Ovarian Cancer Cells

Histone deacetylase 6 (HDAC6) is a unique histone deacetylating enzyme that resides in the cell cytoplasm and is linked to the modulation of several key cancer related responses, including cell proliferation and migration. The promising anti-cancer response of the first-generation HDAC6 catalytic in...

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Bibliographic Details
Main Authors: Ahlam Ali, Fengyu Zhang, Aaron Maguire, Tara Byrne, Karolina Weiner-Gorzel, Stephen Bridgett, Sharon O’Toole, John O’Leary, Caitlin Beggan, Patricia Fitzpatrick, Amanda McCann, Fiona Furlong
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Cancers
Subjects:
HDAC6
HGSOCs
ACY-1215
paclitaxel
cisplatin
survival
Online Access:https://www.mdpi.com/2072-6694/12/12/3734

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