Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

Inducible overexpression of adiponectin receptors highlight the roles of adiponectin-induced ceramidase signaling in lipid and glucose homeostasis

Objective: Adiponectin and the signaling induced by its cognate receptors, AdipoR1 and AdipoR2, have garnered attention for their ability to promote insulin sensitivity and oppose steatosis. Activation of these receptors promotes the deacylation of ceramide, a lipid metabolite that appears to play a...

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Bibliographic Details
Main Authors: William L. Holland, Jonathan Y. Xia, Joshua A. Johnson, Kai Sun, Mackenzie J. Pearson, Ankit X. Sharma, Ezekiel Quittner-Strom, Trevor S. Tippetts, Ruth Gordillo, Philipp E. Scherer
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816303179

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http://www.sciencedirect.com/science/article/pii/S2212877816303179

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