Knockdown of Matrix Metallopeptidase 9 Inhibits Metastasis of Oral Squamous Cell Carcinoma Cells in a Zebrafish Xenograft Model

Knockdown of Matrix Metallopeptidase 9 Inhibits Metastasis of Oral Squamous Cell Carcinoma Cells in a Zebrafish Xenograft Model

Destruction of extracellular matrix (ECM) is one of the basic steps of tumor invasion and metastasis. Matrix metalloproteinase (MMP) 9, a kind of zinc-ion-dependent endopeptidase, can degrade almost all protein components in the ECM, destroy the histological barrier of tumor cell invasion, and play...

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Bibliographic Details
Main Authors:	Jinlin Wen, Panpan Yin, Linwei Li, Guihua Kang, Guozhu Ning, Yu Cao, Feng Gao, Ying Su, Yanlin Wu, Xinyan Zhang
Format:	Article
Language:	English
Published:	Hindawi Limited 2020-01-01
Series:	BioMed Research International
Online Access:	http://dx.doi.org/10.1155/2020/4350783

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