Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Interaction with adipocyte stromal cells induces breast cancer malignancy via S100A7 upregulation in breast cancer microenvironment

Abstract Background Breast adipocytes play important roles in both the development and function of mammary epithelial cells. Therefore, carcinoma–adipose stromal cell (ASC) interactions have been considered pivotal in supporting tumor growth in breast cancer. In addition, it has been demonstrated th...

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Bibliographic Details
Main Authors: Minako Sakurai, Yasuhiro Miki, Kiyoshi Takagi, Takashi Suzuki, Takanori Ishida, Noriaki Ohuchi, Hironobu Sasano
Format: Article
Language:English
Published: BMC 2017-06-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Microenvironment
Cancer-associated adipocytes
S100A7
Online Access:http://link.springer.com/article/10.1186/s13058-017-0863-0

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