Controlling antimicrobial resistance through targeted, vaccine-induced replacement of strains.

Vaccination has proven effective in controlling many infectious diseases. However, differential effectiveness with regard to pathogen genotype is a frequent reason for failures in vaccine development. Often, insufficient immune response is induced to prevent infection by the diversity of existing se...

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Bibliographic Details
Main Authors: Yonas I Tekle, Kaare M Nielsen, Jingzhou Liu, Melinda M Pettigrew, Lauren A Meyers, Alison P Galvani, Jeffrey P Townsend
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3515573?pdf=render