Exploring the Dual Inhibitory Activity of Novel Anthranilic Acid Derivatives towards α-Glucosidase and Glycogen Phosphorylase Antidiabetic Targets: Design, In Vitro Enzyme Assay, and Docking Studies

Exploring the Dual Inhibitory Activity of Novel Anthranilic Acid Derivatives towards α-Glucosidase and Glycogen Phosphorylase Antidiabetic Targets: Design, In Vitro Enzyme Assay, and Docking Studies

A few new anthranilate diamide derivatives, 3a–e, 5a–c and 7a–d, were designed, synthesized, and evaluated for their inhibitory activity against two interesting antidiabetic targets, α-glucosidase and glycogen phosphorylase enzymes. Different instrumental anal...

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Bibliographic Details
Main Author:	Saleh Ihmaid
Format:	Article
Language:	English
Published:	MDPI AG 2018-05-01
Series:	Molecules
Subjects:	antidiabetic anthranilate diamide α-Glucosidase glycogen phosphorylase structure–activity relationships molecular docking
Online Access:	http://www.mdpi.com/1420-3049/23/6/1304

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