Alzheimer's disease related markers, cellular toxicity and behavioral deficits induced six weeks after oligomeric amyloid-β peptide injection in rats.

Alzheimer's disease (AD) is a neurodegenerative pathology associated with aging characterized by the presence of senile plaques and neurofibrillary tangles that finally result in synaptic and neuronal loss. The major component of senile plaques is an amyloid-β protein (Aβ). Recently, we charact...

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Bibliographic Details
Main Authors: Charleine Zussy, Anthony Brureau, Emeline Keller, Stéphane Marchal, Claire Blayo, Brice Delair, Guy Ixart, Tangui Maurice, Laurent Givalois
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534645?pdf=render