Granulin Secreted by the Food-Borne Liver Fluke Opisthorchis viverrini Promotes Angiogenesis in Human Endothelial Cells

Granulin Secreted by the Food-Borne Liver Fluke Opisthorchis viverrini Promotes Angiogenesis in Human Endothelial Cells

The liver fluke Opisthorchis viverrini is a food-borne, zoonotic pathogen endemic to Thailand and adjacent countries in Southeast Asia. The adult developmental stage of the O. viverrini parasite excretes and secretes numerous proteins within the biliary tract including the gall bladder. Lesions caus...

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Bibliographic Details
Main Authors: Brandon Haugen, Shannon E. Karinshak, Victoria H. Mann, Anastas Popratiloff, Alex Loukas, Paul J. Brindley, Michael J. Smout
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Medicine
Subjects:
granulin
parasite
angiogenesis
wound healing
liver cancer
human umbilical vein endothelial cells
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2018.00030/full

Internet

http://journal.frontiersin.org/article/10.3389/fmed.2018.00030/full

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