Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.

Erk1/2 mediates leptin receptor signaling in the ventral tegmental area.

Leptin acts on the ventral tegmental area (VTA) to modulate neuronal function and feeding behavior in rats and mice. To identify the intracellular effectors of the leptin receptor (Lepr), downstream signal transduction events were assessed for regulation by direct leptin infusion. Phosphorylated sig...

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Bibliographic Details
Main Authors: Richard Trinko, Geliang Gan, Xiao-Bing Gao, Robert M Sears, Douglas J Guarnieri, Ralph J DiLeone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3208604?pdf=render

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