Large cell type B primary testicular lymphoma: clinical, histopathological, therapeutic diagnosis and prognostic aspects

• Main Authors: Elena Pérez-Rodriguez, Jesica del Pilar García-Pérez, José Alberto Hermida-Pérez, José Samuel Hernández-Guerra
• Format: Article
• Language: Spanish
• Published: Universidad de Ciencias Médicas de Camagüey 2020-05-01
• Series: Archivo Médico de Camagüey
• Online Access: http://www.revistaamc.sld.cu/index.php/amc/article/view/6990

Background: testicular lymphoma constitutes between 1 and 9 % of testicular tumors; it is the most frequent malignant testicular tumor in men over 50 years of age. The prognosis is reserved due to a great tendency to early systemic spread. The most common clinical presentation is testicular pain on palpation and spontaneous, with increased volume and testicular consistency. Its treatment is based on three fundamental pillars: orchiectomy, chemotherapy and radiotherapy. Objective: to describe a patient with large cell type B testicular lymphoma. Case report: 55-year-old male patient, hypertensive, smoker 10 cigarettes a day, occasional drinker. He goes to consultation due to left testicular volume increase. In the laboratory tests, the lactate dehydrogenase is elevated. Ultrasound Scand: Left testicle with very heterogeneous echogenicity, unstructured parenchyma, no nodular lesions. Diffuse thickening of the epididymis. Increased vascularization. Inguinal radical orchiectomy is performed, the anatomic-pathological diagnosis being diffuse large B cell type lymphoma, it has now been treated with chemotherapy, because he alsopresented bone involvement. But he has evolved favorably. Conclusions: testicular lymphoma is a very rare entity, despite being considered the most common testicular tumor in people over 60 years of age. The majority are diffuse non-Hodgkin lymphomas of high intermediate degree of malignancy and immune-phenotype B. The prognosis is always reserved due to its great tendency to systemic spread. The treatment is based on surgery (radical inguinal orchiectomy), chemotherapy and radiotherapy. DeCS: TESTICULAR NEOPLASMS/surgery; TESTICULAR NEOPLASMS/radiotherapy; LYMPHOMA, LARGE B-CELL, DIFFUSE/diagnosis; ORCHIECTOMY/methods; ANTINEOPLASTIC AGENTS /therapeutic use.