Evaluation of the Protective Effects of Quercetin, Rutin, Naringenin, Resveratrol and Trolox Against Idarubicin-Induced DNA Damage

Evaluation of the Protective Effects of Quercetin, Rutin, Naringenin, Resveratrol and Trolox Against Idarubicin-Induced DNA Damage

PURPOSE. Idarubicin is a synthetic anthracycline anticancer drug widely used in the treatment of some hematological malignancies. The studies in our laboratory have clearly demonstrated that idarubicin can undergo reductive bioactivation by NADPH-cytochrome P450 reductase to free radicals with resul...

Full description

Bibliographic Details
Main Authors:	Haydar Çelik, Emel Arinç
Format:	Article
Language:	English
Published:	Canadian Society for Pharmaceutical Sciences 2010-07-01
Series:	Journal of Pharmacy & Pharmaceutical Sciences
Online Access:	https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/7167

Similar Items

Bioreduction of Idarubicin and Formation of ROS Responsible for DNA Cleavage by NADPH-Cytochrome P450 Reductase and its Potential Role in the Antitumor Effect
by: Haydar Çelik, et al.
Published: (2009-01-01)

Antioxidative activity of resveratrol, 4-hexylresorcinol and trolox and their effects on oxidative DNA damage and the activities of antioxidative enzymes in different cells
by: Chun-Wei Lin, et al.
Published: (1999)

Quercetin and Naringenin Provide Functional and Antioxidant Protection to Stored Boar Semen
by: Eva Tvrdá, et al.
Published: (2020-10-01)

Quercetin and rutin as potential agents antifungal against Cryptococcus spp
by: V. M. Oliveira, et al.

The protective effect of rutin and quercetin on 5-FU-induced hepatotoxicity in rats
by: Volkan Gelen, et al.
Published: (2017-07-01)

The Citrus Flavanone Naringenin Protects Myocardial Cells against Age-Associated Damage
by: Eleonora Da Pozzo, et al.
Published: (2017-01-01)

In Vitro Antioxidant and Anti-Glycation Activity of Resveratrol and Its Novel Triester with Trolox
by: Sebastiano Intagliata, et al.
Published: (2021-12-01)

Quantitative analysis of rutin, quercetin, naringenin, and gallic acid by validated RP- and NP-HPTLC methods for quality control of anti-HBV active extract of Guiera senegalensis
by: Perwez Alam, et al.
Published: (2017-01-01)

Pharmacokinetics of quercetin and rutin in rat plasma and lymph
by: I-Lin Chen, et al.
Published: (2009)

Quercetin and Rutin as Modifiers of Aphid Probing Behavior
by: Katarzyna Stec, et al.
Published: (2021-06-01)

Differential in vitro activity of the DNA topoisomerase inhibitor idarubicin against Trypanosoma rangeli and Trypanosoma cruzi
by: Momodou Jobe, et al.
Published: (2012-11-01)

Antioxidant Activity of Phyllanthus niruri Extract, Rutin and Quercetin
by: Djaja Rusmana, et al.
Published: (2017-08-01)

Study the Activity Of Quercetin and Rutin On Porcine Coronary Arteries
by: Kun-Ho Lee, et al.
Published: (2013)

Antioxidant Effects of Quercetin and Naringenin Are Associated with Impaired Neutrophil Microbicidal Activity
by: Francielli de Cássia Yukari Nishimura, et al.
Published: (2013-01-01)

Insights into idarubicin antimicrobial activity against methicillin-resistant Staphylococcus aureus
by: Pengfei She, et al.
Published: (2020-01-01)

INHIBITION OF WOGONIN, RUTIN AND QUERCETIN ON LIPOPOLYSACCHARIDE-INDUCED INFLAMMATORY RESPENOSES
by: Ho-Chun Huang, et al.
Published: (2001)

Binding and antiplatelet activity of quercetin, rutin, diosmetin, and diosmin flavonoids
by: Cristina Zaragozá, et al.
Published: (2021-09-01)

The Redox Reactions of Quercetin、Rutin and Taxifolin with Transition Metal Complexes
by: Wei-Lin Chen, et al.
Published: (2010)

COMPARISON OF INOTROPIC AND ANTIARRHYTHMIC ACTIVITY OF FLAVONOIDS — QUERCETIN, RUTIN AND (+)-CATECHIN
by: Sh. S. Khushmatov, et al.
Published: (2015-11-01)

Differential Modulation of the Phospholipidome of Proinflammatory Human Macrophages by the Flavonoids Quercetin, Naringin and Naringenin
by: Tiago A. Conde, et al.
Published: (2020-07-01)

Direct actions of the flavonoids naringenin, quercetin and genistein on rat cardiac and vascular muscles
by: Loipa Galán-Martínez, et al.
Published: (2018-05-01)

Protective role of antioxidant vitamin E and catechin on idarubicin-induced cardiotoxicity in rats
by: Kalender S., et al.
Published: (2002-01-01)

Antigenotoxic potential of rutin and quercetin in Swiss mice exposed to gamma radiation
by: Shrikant L Patil, et al.
Published: (2014-10-01)

Effect of flavonoids rutin and quercetin in peripheral neuropathy induced sensitive oxaliplatin
by: Maria Isabel Carneiro de Azevedo
Published: (2012)

The Effect of Resveratrol and Quercetin on Colon Cancer
by: Parvin Ekhlaspour, et al.
Published: (2021-03-01)

Action mechanisms of Idarubicin as an Inducer for Interferon Signaling
by: Pei-Jung Wu, et al.
Published: (2015)

Mechanistic study of Idarubicin-induced interferon-signaling
by: Min-Tsz Huang, et al.
Published: (2017)

Homocysteine and DNA damage in cultured cells: protection by resveratrol and potentiation by s-adenosylhomocysteine
by: Pei-ying Lin, et al.
Published: (2003)

Resveratrol Protects against Methylglyoxal-Induced Hyperglycemia and Pancreatic Damage In Vivo
by: An-Sheng Cheng, et al.
Published: (2015-04-01)

Opposing Effect of Naringenin and Quercetin on the Junctional Compartment of MDCK II Cells to Modulate the Tight Junction
by: Mio Nakashima, et al.
Published: (2020-10-01)

An exploratory analysis on the toxicity & safety profile of Polyherbal combination of curcumin, quercetin and rutin
by: Reshu Tiwari, et al.
Published: (2020-12-01)

Recent progress in simultaneous estimation of rutin, quercetin and liquiritin in Cocculus hirsutus by HPTLC
by: V. Patil, et al.
Published: (2015-07-01)

Addition of rutin/quercetin mixture to spreadable processed cheese: antioxidant and textural characteristics
by: Libor Červenka, et al.
Published: (2018-03-01)

Impact of Fermentable Fibres on the Colonic Microbiota Metabolism of Dietary Polyphenols Rutin and Quercetin
by: Bahareh Mansoorian, et al.
Published: (2019-01-01)

Neuroprotective Effects of Rutin and Quercetin Flavonoids in Glaucium corniculatum Methanol and Water Extracts
by: Fatma Gonca Koçancı, et al.
Published: (2017-12-01)

The Beneficial Effects of Quercetin, Curcumin, and Resveratrol in Obesity
by: Yueshui Zhao, et al.
Published: (2017-01-01)

Quercetin with resveratrol liposome formulation and micrometer crystals attenuated particulate matter-induced keratinocyte damage
by: Chiung-wen Hsu, et al.
Published: (2018)

Resveratrol and Quercetin as Regulators of Inflammatory and Purinergic Receptors to Attenuate Liver Damage Associated to Metabolic Syndrome
by: Agustina Cano-Martínez, et al.
Published: (2021-08-01)

Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats
by: Ramalingayya GV, et al.
Published: (2017-03-01)

Signal pathways implicated in idarubicin-induced antiviral state
by: Guan-Gun Huang, et al.
Published: (2018)