Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma

Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma

It is well established that the PTEN (Phosphatase and Tensin Homolog) mutant is a frequently mutated gene found in clear cell renal cell carcinoma (ccRCC), making it a potential biomarker for individualized treatment opinions. Here, in the present study, we designed a method to evaluate the signific...

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Bibliographic Details
Main Authors: Caibin Fan, Chunchun Zhao, Fei Wang, Shugen Li, Jianqing Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Oncology
Subjects:
clear cell renal cell carcinoma
PTEN mutation
TCGA
RNA sequencing
bioinformatics analysis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00357/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00357/full

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