Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens
Designing efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-12-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-19911-6 |
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Article |
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doaj-a98aceb5b7574affba0711cdddc4bbe42021-05-11T08:07:44ZengNature Publishing GroupNature Communications2041-17232020-12-0111111010.1038/s41467-020-19911-6Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogensEstefania Nunez-Bajo0Alexander Silva Pinto Collins1Michael Kasimatis2Yasin Cotur3Tarek Asfour4Ugur Tanriverdi5Max Grell6Matti Kaisti7Guglielmo Senesi8Karen Stevenson9Firat Güder10Department of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonDepartment of Bioengineering, Imperial College LondonMoredun Research Institute, Pentlands Science Park, Bush LoanDepartment of Bioengineering, Imperial College LondonDesigning efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of nucleic acids quantitatively in real-time.https://doi.org/10.1038/s41467-020-19911-6 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Estefania Nunez-Bajo Alexander Silva Pinto Collins Michael Kasimatis Yasin Cotur Tarek Asfour Ugur Tanriverdi Max Grell Matti Kaisti Guglielmo Senesi Karen Stevenson Firat Güder |
| spellingShingle |
Estefania Nunez-Bajo Alexander Silva Pinto Collins Michael Kasimatis Yasin Cotur Tarek Asfour Ugur Tanriverdi Max Grell Matti Kaisti Guglielmo Senesi Karen Stevenson Firat Güder Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens Nature Communications |
| author_facet |
Estefania Nunez-Bajo Alexander Silva Pinto Collins Michael Kasimatis Yasin Cotur Tarek Asfour Ugur Tanriverdi Max Grell Matti Kaisti Guglielmo Senesi Karen Stevenson Firat Güder |
| author_sort |
Estefania Nunez-Bajo |
| title |
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens |
| title_short |
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens |
| title_full |
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens |
| title_fullStr |
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens |
| title_full_unstemmed |
Disposable silicon-based all-in-one micro-qPCR for rapid on-site detection of pathogens |
| title_sort |
disposable silicon-based all-in-one micro-qpcr for rapid on-site detection of pathogens |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-12-01 |
| description |
Designing efficient, rapid and low-cost diagnostic technologies targeting nucleic acids remains a challenge. Here the authors present a disposable silicon-based integrated Point-of-Need transducer produced in a standard wet lab and able to chemically-amplify and detect pathogen-specific sequences of nucleic acids quantitatively in real-time. |
| url |
https://doi.org/10.1038/s41467-020-19911-6 |
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