Pin1 modulates the type 1 immune response.
BACKGROUND/ABSTRACT: Immune responses initiated by T cell receptor (TCR) and costimulatory molecule mediated signaling culminate in maximal cytokine mRNA production and stability. The transcriptional responses to co-stimulatory T cell signalling involve calcineurin and NF-AT, which can be antagonize...
Main Authors: | Stephane Esnault, Ruedi K Braun, Zhong-Jian Shen, Zhuzai Xiang, Erika Heninger, Robert B Love, Matyas Sandor, James S Malter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-02-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC1790862?pdf=render |
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