Pin1 modulates the type 1 immune response.

BACKGROUND/ABSTRACT: Immune responses initiated by T cell receptor (TCR) and costimulatory molecule mediated signaling culminate in maximal cytokine mRNA production and stability. The transcriptional responses to co-stimulatory T cell signalling involve calcineurin and NF-AT, which can be antagonize...

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Bibliographic Details
Main Authors: Stephane Esnault, Ruedi K Braun, Zhong-Jian Shen, Zhuzai Xiang, Erika Heninger, Robert B Love, Matyas Sandor, James S Malter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1790862?pdf=render