The potency of secondary metabolites from traditional medicine plants as anti cancer agent

• Main Author: Mai Efdi
• Format: Article
• Language: English
• Published: Faculty of Medicine Andalas University 2014-12-01
• Series: Majalah Kedokteran Andalas
• Subjects: traditional medicin plants; Annonaceae; Melliaceae; anti cancer-agent
• Online Access: http://jurnalmka.fk.unand.ac.id/index.php/art/article/view/217

<p>The seconday metabolites from traditional medicine plants have played an important role in<br />cancer treatment. Exploration of natural active compounds from medicinal plants for cancer<br />treatment has attracted substantial attention worldwide. Several secondary metabolites that<br />were isolated fom the plants, such as vincristne, vinblastine, campthothecins, have been used<br />have been used clinically for over 40 years. Numerous techniques have been developed<br />to obtain compounds for drug discovery including isolation from plants, synthetic chemistry,<br />screening bioassays. As part of efforts to discover phytochemicals as anticancer agent, our<br />group were isolated several compunds mainly from Annonaceae and Melliaceae family that<br />showed active againts human leukemia HL-60 cells.<br /><br /></p>