Hydrogen peroxide decreases the survival rate of HeLa cells with stable knockdown of survival motor neuron protein

Hydrogen peroxide decreases the survival rate of HeLa cells with stable knockdown of survival motor neuron protein

The mutations of survival motor neuron (SMN) gene result in spinal muscular atrophy (SMA), a common neurodegenerative disease. Some of the motor neurons undergoing cell death is the predominant characteristic in SMA pathology. However, the viability and sensitivity to stresses of other cell types al...

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Bibliographic Details
Main Authors: Ting-Yuan Liu, Chung-Yee Yuo, Cheng-Hsing Kao, Chao-Neng Tseng, Yuh-Jyh Jong, Jan-Gowth Chang, Shou-Mei Wu, Yung-Fu Chang, 劉鼎元, 游仲逸, 高振興, 曾昭能, 鐘育志, 張建國, 吳秀梅, 張永福
Format: Article
Language:English
Published: Wiley 2011-03-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
Cell proliferation
Inducible knockdown
Oxidative stress
Survival of motor neuron
Online Access:http://www.sciencedirect.com/science/article/pii/S1607551X10000355

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http://www.sciencedirect.com/science/article/pii/S1607551X10000355

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