Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

Hepatitis B viral core protein disrupts human host gene expression by binding to promoter regions

<p>Abstract</p> <p>Background</p> <p>The core protein (HBc) of hepatitis B virus (HBV) has been implicated in the malignant transformation of chronically-infected hepatocytes and displays pleiotropic functions, including RNA- and DNA-binding activities. However, the mec...

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Bibliographic Details
Main Authors: Guo Yanhai, Kang Wei, Lei Xiaoying, Li Yongnian, Xiang An, Liu Yonglan, Zhao Jinrong, Zhang Ju, Yan Zhen
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Genomics
Subjects:
Hepatitis B virus
Hepatitis B core protein
Chromatin immunoprecipitation microarray
ChIP-on-chip
Gene expression
DNA-protein interaction
Online Access:http://www.biomedcentral.com/1471-2164/13/563

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