Mitochondrial concept of leukemogenesis: key role of oxygen-peroxide effects

<p>Abstract</p> <p>Background and hypothesis</p> <p>The high sensitivity of hematopoietic cells, especially stem cells, to radiation and to pro-oxidative and other leukemogenic agents is related to certain of their morphological and metabolic features. It is attributabl...

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Bibliographic Details
Main Authors: Ismailov Bolat, Ismailov Sanzhar B, Lyu Boris N, Lyu Marina B
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/5/1/23