The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

The catalytic subunit of Plasmodium falciparum casein kinase 2 is essential for gametocytogenesis

Hitz et al. describe the role of the protein kinase PfCK2α in the development of the human malaria parasite Plasmodium falciparum. Using mutant parasites, they show that PfCK2α is not only essential for asexual but also sexual development of P. falciparum blood stage parasites, and hence it may hold...

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Bibliographic Details
Main Authors: Eva Hitz, Olivia Grüninger, Armin Passecker, Matthias Wyss, Christian Scheurer, Sergio Wittlin, Hans-Peter Beck, Nicolas M. B. Brancucci, Till S. Voss
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-01873-0
Description
Summary:Hitz et al. describe the role of the protein kinase PfCK2α in the development of the human malaria parasite Plasmodium falciparum. Using mutant parasites, they show that PfCK2α is not only essential for asexual but also sexual development of P. falciparum blood stage parasites, and hence it may hold promise as a potential target for antimalarial drugs.
ISSN:2399-3642

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