Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: Evidence from a novel CARNS1 knockout rat model

Histidine dipeptides are key regulators of excitation-contraction coupling in cardiac muscle: Evidence from a novel CARNS1 knockout rat model

Histidine-containing dipeptides (HCDs) are abundantly expressed in striated muscles. Although important properties have been ascribed to HCDs, including H+ buffering, regulation of Ca2+ transients and protection against oxidative stress, it remains unknown whether they play relevant functions in viv...

Full description

Bibliographic Details
Main Authors: Lívia de Souza Gonçalves, Lucas Peixoto Sales, Tiemi Raquel Saito, Juliane Cruz Campos, Alan Lins Fernandes, José Natali, Leonardo Jensen, Alexandre Arnold, Lisley Ramalho, Luiz Roberto Grassmann Bechara, Marcos Vinicius Esteca, Isis Correa, Diogo Sant'Anna, Alexandre Ceroni, Lisete Compagno Michelini, Bruno Gualano, Walcy Teodoro, Victor Henrique Carvalho, Bianca Scigliano Vargas, Marisa Helena Gennari Medeiros, Igor Luchini Baptista, Maria Cláudia Irigoyen, Craig Sale, Julio Cesar Batista Ferreira, Guilherme Giannini Artioli
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Redox Biology
Subjects:
Carnosine
Cardiac dysfunction
Carnosine synthase
Skeletal muscle
Cardiac muscle
Calcium transient
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721001749

Internet

http://www.sciencedirect.com/science/article/pii/S2213231721001749

Similar Items