A synthetic form of frizzled 8-associated antiproliferative factor enhances p53 stability through USP2a and MDM2.
Frizzled 8-associated Antiproliferative Factor (APF) is a sialoglycopeptide urinary biomarker of interstitial cystitis/painful bladder syndrome (IC/PBS), a chronic condition of unknown etiology with variable symptoms that generally include pelvic and/or perineal pain, urinary frequency, and urgency....
Main Authors: | Jayoung Kim, Susan K Keay, Sungyong You, Massimo Loda, Michael R Freeman |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3516501?pdf=render |
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