Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34<sup>+</sup> Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia

Altered Spatial Composition of the Immune Cell Repertoire in Association to CD34<sup>+</sup> Blasts in Myelodysplastic Syndromes and Secondary Acute Myeloid Leukemia

<i>Background</i>: Myelodysplastic syndromes (MDS) are caused by a stem cell failure and often include a dysfunction of the immune system. However, the relationship between spatial immune cell distribution within the bone marrow (BM), in relation to genetic features and the course of dis...

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Bibliographic Details
Main Authors: Marcus Bauer, Christoforos Vaxevanis, Haifa Kathrin Al-Ali, Nadja Jaekel, Christin Le Hoa Naumann, Judith Schaffrath, Achim Rau, Barbara Seliger, Claudia Wickenhauser
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
MDS
immune cell repertoire
prognosis
multiplex immunohistochemistry
CD34<sup>+</sup> blasts
Online Access:https://www.mdpi.com/2072-6694/13/2/186

Internet

https://www.mdpi.com/2072-6694/13/2/186

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