Solid-liquid systems for the hydrolysis of glycoalkaloids from potato (Solanum tuberosum L) tuber sprouts and solanidine isolation

• Main Authors: Nikolić Nada Č., Stanković Mihajlo Z., Cakić Milorad D.
• Format: Article
• Language: English
• Published: Association of Chemical Engineers of Serbia 2003-01-01
• Series: Hemijska Industrija
• Subjects: Potato sprouts; Glycoalkaloids; Hydrolysis; Solanidine; Isolation
• Online Access: http://www.doiserbia.nb.rs/img/doi/0367-598X/2003/0367-598X0306288N.pdf

Solanidine (C17H43O/V) is a steroidal aglycone of glycoalkaloids and an important precursor for the synthesis of hormones and some pharmacologically active compounds. Glycoalkaloids are hydrolysed by mineral acid yielding solanidine and a carbohydrate moiety. In this paper the kinetics of hydrolysis of glycoalkaloids from potato (Solanum tuberosum L) tuber sprouts by using solid-liquid systems were studied as well as solanidine isolation from the liquid phase of the system. The dried and milled tuber sprouts of potato were used as the solid phase and solutions of hydrochloric acid of different concentration in 96 % vol. ethanol, mixed with chloroform in a volume ratio of 2:3, 1:1, 3:2 and 4:1, were used as the liquid phase. The aim of the paper was to choose the optimal concentration of hydrochloric acid in ethanol, the volume ratio of hydrochloric acid in ethanol to chloroform in the liquid phase and the time for solanidine hydrolytic extraction, as well as to isolate solanidine from the liquid phase.