Combination of Doxorubicin and Berberine Generated Synergistic Anticancer Effect on Breast Cancer Cells Through Down-regulation of Nanog and miRNA-21 Gene Expression

Combination of Doxorubicin and Berberine Generated Synergistic Anticancer Effect on Breast Cancer Cells Through Down-regulation of Nanog and miRNA-21 Gene Expression

Background: Our purpose was to investigate the effect of berberine (BER) and doxorubicin (DOX) on the expression of stem cell markers Nanog and microRNA- 21 in MCF-7 cells. Methods: The study was an in vitro study employing the human breast cancer cell line MCF-7 that was divided into four group...

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Bibliographic Details
Main Authors: Samia A. Ebeid, Nadia A. Abd El Moneim, Hossam El-Din M. Ghoneim, Sanaa A. El-Benhawy, Samah E. Ismail
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2020-07-01
Series:Middle East Journal of Cancer
Subjects:
breast cancer
nanog
mirna-21
doxorubicin
berberine
Online Access:https://mejc.sums.ac.ir/article_46718.html

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