Adenosine signaling mediates osteogenic differentiation of human embryonic stem cells on mineralized matrices

Adenosine signaling mediates osteogenic differentiation of human embryonic stem cells on mineralized matrices

Human embryonic stem cells (hESCs) are attractive cell sources for tissue engineering and regenerative medicine due to their self-renewal and differentiation ability. Design of biomaterials with an intrinsic ability that promotes hESC differentiation to the targeted cell type boasts significant adva...

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Bibliographic Details
Main Authors: Vikram eRao, Yu-Ru V. Shih, Heemin eKang, Harsha eKabra, Shyni eVarghese
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
human embryonic stem cells
Calcium phosphate
Osteogenic differentiation
A2B adenosine receptor
Mineralized matrix
Online Access:http://journal.frontiersin.org/Journal/10.3389/fbioe.2015.00185/full

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