Ganglioside Metabolism in a Transgenic Mouse Model of Alzheimer's Disease: Expression of Chol-1α Antigens in the Brain
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with the biochemical pathology of neurological d...
Main Authors: | Toshio Ariga, Makoto Yanagisawa, Chandramohan Wakade, Susumu Ando, Jerry J Buccafusco, Michael P McDonald, Robert K Yu |
---|---|
Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2010-08-01
|
Series: | ASN Neuro |
Online Access: | https://doi.org/10.1042/AN20100021 |
Similar Items
-
Anti-Chol-1 antigen, GQ1bα, antibodies are associated with Alzheimer's disease.
by: Toshio Ariga, et al.
Published: (2013-01-01) -
The Pathological Roles of Ganglioside Metabolism in Alzheimer's Disease: Effects of Gangliosides on Neurogenesis
by: Toshio Ariga, et al.
Published: (2011-01-01) -
Brain Gangliosides of a Transgenic Mouse Model of Alzheimer's Disease with Deficiency in GD3-Synthase: Expression of Elevated Levels of a Cholinergic-Specific Ganglioside, GT1aα
by: Toshio Ariga, et al.
Published: (2013-04-01) -
Thematic Review Series: Sphingolipids. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease—a review*1
by: Toshio Ariga, et al.
Published: (2008-06-01) -
Cytotoxic Effects of G Ganglioside and Amyloid β-Peptide on Mouse Embryonic Neural Stem Cells
by: Makoto Yanagisawa, et al.
Published: (2010-01-01)