SRSF1 regulates exosome microRNA enrichment in human cancer cells

SRSF1 regulates exosome microRNA enrichment in human cancer cells

Abstract Background Exosomes are extracellular vesicles containing a variety of biological molecules including microRNAs (miRNAs). We have recently demonstrated that certain miRNA species are selectively and highly enriched in pancreatic cancer exosomes with miR-1246 being the most abundant. Exosome...

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Bibliographic Details
Main Authors: Yi-Fan Xu, Xiaohui Xu, Amy Gin, Jean D. Nshimiyimana, Blaine H. M. Mooers, Massimo Caputi, Bethany N. Hannafon, Wei-Qun Ding
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Cell Communication and Signaling
Subjects:
SRSF1
Exosome
miRNA
miR-1246
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s12964-020-00615-9

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