VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice.

Asthma is a chronic inflammatory condition of the lower respiratory tract associated with airway hyperreactivity and mucus obstruction in which a majority of cases are due to an allergic response to environmental allergens. Glucocorticoids such as prednisone have been standard treatment for many inf...

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Bibliographic Details
Main Authors: Jesse M Damsker, Blythe C Dillingham, Mary C Rose, Molly A Balsley, Christopher R Heier, Alan M Watson, Erik J Stemmy, Roslyn A Jurjus, Tony Huynh, Kathleen Tatem, Kitipong Uaesoontrachoon, Dana M Berry, Angela S Benton, Robert J Freishtat, Eric P Hoffman, John M McCall, Heather Gordish-Dressman, Stephanie L Constant, Erica K M Reeves, Kanneboyina Nagaraju
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646769?pdf=render