Nitric oxide alters hyaluronan deposition by airway smooth muscle cells.
Asthma is a chronic inflammatory disease that is known to cause changes in the extracellular matrix, including changes in hyaluronan (HA) deposition. However, little is known about the factors that modulate its deposition or the potential consequences. Asthmatics with high levels of exhaled nitric o...
Main Authors: | Alana K Majors, Ritu Chakravarti, Lisa M Ruple, Rachel Leahy, Dennis J Stuehr, Mark Lauer, Serpil C Erzurum, Allison Janocha, Mark A Aronica |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2018-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0200074 |
Similar Items
-
The Rise and Fall of Hyaluronan in Respiratory Diseases
by: Mark E. Lauer, et al.
Published: (2015-01-01) -
Chronic asthma and Mesenchymal stem cells: Hyaluronan and airway remodeling
by: Benjamin D. Goldstein, et al.
Published: (2017-08-01) -
Defective Resensitization in Human Airway Smooth Muscle Cells Evokes β-Adrenergic Receptor Dysfunction in Severe Asthma.
by: Manveen K Gupta, et al.
Published: (2015-01-01) -
An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling
by: Arnab Ghosh, et al.
Published: (2021-02-01) -
A novel method for pulmonary research: Assessment of bioenergetic function at the air–liquid interface
by: Weiling Xu, et al.
Published: (2014-01-01)