A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India

A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India

Potassium is an important intracellular cation responsible for action potential generation and normal functioning of muscles. Hypokalemia and hyperkalemia are both dangerous as they cause life threatening cardiac arrhythmias. Piperacillin tazobactam is a commonly used beta-lactam and beta-lactamase...

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Main Authors: Kunder SK, Chogtu B, Avinash A, Pathak A, Patil N, Adiga S
Format: Article
Language:English
Published: Light House Polyclinic Mangalore 2016-01-01
Series:Online Journal of Health & Allied Sciences
Subjects:
Potassium
Ureidopenicillin
Pharmacovigilance
Beta-Lactam
Beta-Lactamase inhibitor
Online Access:http://www.ojhas.org/issue56/2015-4-17.html
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spelling doaj-a8e70024933746b08db09743655efdda2020-11-24T22:25:16ZengLight House Polyclinic Mangalore Online Journal of Health & Allied Sciences0972-59972016-01-01144A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South IndiaKunder SK0Chogtu B1Avinash A2Pathak A3Patil N4Adiga S5Dept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaDept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaDept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaDept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaDept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaDept. of Pharmacology, Kasturba Medical College, Manipal University, Manipal-576104, IndiaPotassium is an important intracellular cation responsible for action potential generation and normal functioning of muscles. Hypokalemia and hyperkalemia are both dangerous as they cause life threatening cardiac arrhythmias. Piperacillin tazobactam is a commonly used beta-lactam and beta-lactamase inhibitor combination for complicated abdominal and urinary tract infections. Under pharmacovigilance programme of India, few cases of hypokalemia which were attributed to piperacillin tazobactam therapy were reported. This is a case series of 10 patients who developed hypokalemia secondary to piperacillin tazobactam therapy.http://www.ojhas.org/issue56/2015-4-17.htmlPotassiumUreidopenicillinPharmacovigilanceBeta-LactamBeta-Lactamase inhibitor
collection DOAJ
language English
format Article
sources DOAJ
author Kunder SK
Chogtu B
Avinash A
Pathak A
Patil N
Adiga S
spellingShingle Kunder SK
Chogtu B
Avinash A
Pathak A
Patil N
Adiga S
A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
Online Journal of Health & Allied Sciences
Potassium
Ureidopenicillin
Pharmacovigilance
Beta-Lactam
Beta-Lactamase inhibitor
author_facet Kunder SK
Chogtu B
Avinash A
Pathak A
Patil N
Adiga S
author_sort Kunder SK
title A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
title_short A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
title_full A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
title_fullStr A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
title_full_unstemmed A Case Series of Piperacillin-Tazobactam Induced Hypokalemia in a Tertiary Care Hospital in South India
title_sort case series of piperacillin-tazobactam induced hypokalemia in a tertiary care hospital in south india
publisher Light House Polyclinic Mangalore
series Online Journal of Health & Allied Sciences
issn 0972-5997
publishDate 2016-01-01
description Potassium is an important intracellular cation responsible for action potential generation and normal functioning of muscles. Hypokalemia and hyperkalemia are both dangerous as they cause life threatening cardiac arrhythmias. Piperacillin tazobactam is a commonly used beta-lactam and beta-lactamase inhibitor combination for complicated abdominal and urinary tract infections. Under pharmacovigilance programme of India, few cases of hypokalemia which were attributed to piperacillin tazobactam therapy were reported. This is a case series of 10 patients who developed hypokalemia secondary to piperacillin tazobactam therapy.
topic Potassium
Ureidopenicillin
Pharmacovigilance
Beta-Lactam
Beta-Lactamase inhibitor
url http://www.ojhas.org/issue56/2015-4-17.html
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