Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

The relationships between β-amyloid (Aβ), tau and neurodegeneration within Alzheimer's Disease pathogenesis are not fully understood. To explore these associations in vivo, we evaluated 30 Aβ PET-positive patients (mean±sd age 62.4±8.3) with mild probable AD and 12 Aβ PET-negative healthy contr...

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Main Authors: Leonardo Iaccarino, Gautam Tammewar, Nagehan Ayakta, Suzanne L. Baker, Alexandre Bejanin, Adam L. Boxer, Maria Luisa Gorno-Tempini, Mustafa Janabi, Joel H. Kramer, Andreas Lazaris, Samuel N. Lockhart, Bruce L. Miller, Zachary A. Miller, James P. O'Neil, Rik Ossenkoppele, Howard J. Rosen, Daniel R. Schonhaut, William J. Jagust, Gil D. Rabinovici
Format: Article
Language:English
Published: Elsevier 2018-01-01
Series:NeuroImage: Clinical
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158217302309

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