Establishing an adjusted p-value threshold to control the family-wide type 1 error in genome wide association studies

<p>Abstract</p> <p>Background</p> <p>By assaying hundreds of thousands of single nucleotide polymorphisms, genome wide association studies (GWAS) allow for a powerful, unbiased review of the entire genome to localize common genetic variants that influence health and dis...

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Bibliographic Details
Main Authors: Bailey-Wilson Joan E, Holmes Taura N, Gillanders Elizabeth M, Duggal Priya
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/516