A Multi-Step miRNA-mRNA Regulatory Network Construction Approach Identifies Gene Signatures Associated with Endometrioid Endometrial Carcinoma

A Multi-Step miRNA-mRNA Regulatory Network Construction Approach Identifies Gene Signatures Associated with Endometrioid Endometrial Carcinoma

We aimed to identify endometrioid endometrial carcinoma (EEC)-related gene signatures using a multi-step miRNA-mRNA regulatory network construction approach. Pathway analysis showed that 61 genes were enriched on many carcinoma-related pathways. Among the 14 highest scoring gene signatures, six gene...

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Bibliographic Details
Main Authors: Hanzhen Xiong, Qiulian Li, Ruichao Chen, Shaoyan Liu, Qiongyan Lin, Zhongtang Xiong, Qingping Jiang, Linlang Guo
Format: Article
Language:English
Published: MDPI AG 2016-06-01
Series:Genes
Subjects:
CPEB1
endometrial carcinoma
miRNA targets
protein-protein interaction network
EMT
p53
Online Access:http://www.mdpi.com/2073-4425/7/6/26

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