The Gut Microbiome as a Major Regulator of the Gut-Skin Axis

The Gut Microbiome as a Major Regulator of the Gut-Skin Axis

The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main...

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Bibliographic Details
Main Authors: Iman Salem, Amy Ramser, Nancy Isham, Mahmoud A. Ghannoum
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Microbiology
Subjects:
gut microbiome
skin homeostasis
acne vulgaris
atopic dermatitis
psoriasis
probiotics
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01459/full
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spelling doaj-a8aa0041fe14412ea17fab1307f8a08c2020-11-24T21:20:11ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2018-07-01910.3389/fmicb.2018.01459382698The Gut Microbiome as a Major Regulator of the Gut-Skin AxisIman Salem0Amy Ramser1Nancy Isham2Mahmoud A. Ghannoum3Mahmoud A. Ghannoum4Center for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, OH, United StatesDermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, United StatesCenter for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, OH, United StatesCenter for Medical Mycology, Department of Dermatology, Case Western Reserve University, Cleveland, OH, United StatesDermatology, University Hospitals Cleveland Medical Center, Cleveland, OH, United StatesThe adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions.https://www.frontiersin.org/article/10.3389/fmicb.2018.01459/fullgut microbiomeskin homeostasisacne vulgarisatopic dermatitispsoriasisprobiotics
collection DOAJ
language English
format Article
sources DOAJ
author Iman Salem
Amy Ramser
Nancy Isham
Mahmoud A. Ghannoum
Mahmoud A. Ghannoum
spellingShingle Iman Salem
Amy Ramser
Nancy Isham
Mahmoud A. Ghannoum
Mahmoud A. Ghannoum
The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
Frontiers in Microbiology
gut microbiome
skin homeostasis
acne vulgaris
atopic dermatitis
psoriasis
probiotics
author_facet Iman Salem
Amy Ramser
Nancy Isham
Mahmoud A. Ghannoum
Mahmoud A. Ghannoum
author_sort Iman Salem
title The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_short The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_full The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_fullStr The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_full_unstemmed The Gut Microbiome as a Major Regulator of the Gut-Skin Axis
title_sort gut microbiome as a major regulator of the gut-skin axis
publisher Frontiers Media S.A.
series Frontiers in Microbiology
issn 1664-302X
publishDate 2018-07-01
description The adult intestine hosts a myriad of diverse bacterial species that reside mostly in the lower gut maintaining a symbiosis with the human habitat. In the current review, we describe the neoteric advancement in our comprehension of how the gut microbiota communicates with the skin as one of the main regulators in the gut-skin axis. We attempted to explore how this potential link affects skin differentiation and keratinization, its influence on modulating the cutaneous immune response in various diseases, and finally how to take advantage of this communication in the control of different skin conditions.
topic gut microbiome
skin homeostasis
acne vulgaris
atopic dermatitis
psoriasis
probiotics
url https://www.frontiersin.org/article/10.3389/fmicb.2018.01459/full
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