Current practices and guidelines for clinical next-generation sequencing oncology testing

Current practices and guidelines for clinical next-generation sequencing oncology testing

Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadthgenomic of information available to oncologists and their patients. This review will explore the ways in which this new technologyis currently applied to bolster care for patient...

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Bibliographic Details
Main Author: Samuel P. Strom
Format: Article
Language:English
Published: China Anti-Cancer Association 2016-03-01
Series:Cancer Biology & Medicine
Subjects:
Cancer genomics
next-generation sequencing
molecular diagnostics
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/917
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spelling doaj-a8a90da566a24f14a44fb6fe4c614dda2020-11-25T02:07:50ZengChina Anti-Cancer AssociationCancer Biology & Medicine2095-39412095-39412016-03-0113131110.20892/j.issn.2095-3941.2016.00042016000004Current practices and guidelines for clinical next-generation sequencing oncology testingSamuel P. Strom0Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USANext-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadthgenomic of information available to oncologists and their patients. This review will explore the ways in which this new technologyis currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices andguidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.http://www.cancerbiomed.org/index.php/cocr/article/view/917Cancer genomicsnext-generation sequencingmolecular diagnostics
collection DOAJ
language English
format Article
sources DOAJ
author Samuel P. Strom
spellingShingle Samuel P. Strom
Current practices and guidelines for clinical next-generation sequencing oncology testing
Cancer Biology & Medicine
Cancer genomics
next-generation sequencing
molecular diagnostics
author_facet Samuel P. Strom
author_sort Samuel P. Strom
title Current practices and guidelines for clinical next-generation sequencing oncology testing
title_short Current practices and guidelines for clinical next-generation sequencing oncology testing
title_full Current practices and guidelines for clinical next-generation sequencing oncology testing
title_fullStr Current practices and guidelines for clinical next-generation sequencing oncology testing
title_full_unstemmed Current practices and guidelines for clinical next-generation sequencing oncology testing
title_sort current practices and guidelines for clinical next-generation sequencing oncology testing
publisher China Anti-Cancer Association
series Cancer Biology & Medicine
issn 2095-3941
2095-3941
publishDate 2016-03-01
description Next-generation sequencing (NGS) has been rapidly integrated into molecular pathology, dramatically increasing the breadthgenomic of information available to oncologists and their patients. This review will explore the ways in which this new technologyis currently applied to bolster care for patients with solid tumors and hematological malignancies, focusing on practices andguidelines for assessing the technical validity and clinical utility of DNA variants identified during clinical NGS oncology testing.
topic Cancer genomics
next-generation sequencing
molecular diagnostics
url http://www.cancerbiomed.org/index.php/cocr/article/view/917
work_keys_str_mv AT samuelpstrom currentpracticesandguidelinesforclinicalnextgenerationsequencingoncologytesting
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