Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response

Genome-Wide Dynamic Evaluation of the UV-Induced DNA Damage Response

Genetic screens in Saccharomyces cerevisiae have allowed for the identification of many genes as sensors or effectors of DNA damage, typically by comparing the fitness of genetic mutants in the presence or absence of DNA-damaging treatments. However, these static screens overlook the dynamic nature...

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Bibliographic Details
Main Authors: Erica Silva, Manuel Michaca, Brenton Munson, Gordon J. Bean, Philipp A. Jaeger, Katherine Licon, Elizabeth A. Winzeler, Trey Ideker
Format: Article
Language:English
Published: Oxford University Press 2020-09-01
Series:G3: Genes, Genomes, Genetics
Subjects:
ultraviolet radiation response
dna damage response
high-throughput screen
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.120.401417

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