Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease

Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease

Meniere’s disease (MD) is a rare disorder characterized by episodic vertigo, sensorineural hearing loss, tinnitus, and aural fullness. It is associated with a fluid imbalance between the secretion of endolymph in the cochlear duct and its reabsorption into the subarachnoid space, leading to an accum...

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Bibliographic Details
Main Authors: Lidia Frejo, Teresa Requena, Satoshi Okawa, Alvaro Gallego-Martinez, Manuel Martinez-Bueno, Ismael Aran, Angel Batuecas-Caletrio, Jesus Benitez-Rosario, Juan M. Espinosa-Sanchez, Jesus José Fraile-Rodrigo, Ana María García-Arumi, Rocío González-Aguado, Pedro Marques, Eduardo Martin-Sanz, Nicolas Perez-Fernandez, Paz Pérez-Vázquez, Herminio Perez-Garrigues, Sofía Santos-Perez, Andres Soto-Varela, Maria C. Tapia, Gabriel Trinidad-Ruiz, Antonio del Sol, Marta E. Alarcon Riquelme, Jose A. Lopez-Escamez
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Immunology
Subjects:
TNFRSF12A
NFKB1
TWEAK/Fn14 pathway
NF-κB signaling
vertigo
sensorineural hearing loss
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01739/full

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