The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy

The expression of P16 and S100 associated with elastin degradation and fibrosis of the Ligamentum Flavum hypertrophy

Abstract Background One of the characteristics of lumbar spinal stenosis (LSS) is elastin degradation and fibrosis in the ligamentum flavum (LF). However, the biochemical factors that cause these histologic changes is unclear. P16 and S100 participate in scar formation and collagen development in wo...

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Bibliographic Details
Main Authors: Wei Hu, Shunli Kan, Guang Liu, Zegang Cao, Rusen Zhu
Format: Article
Language:English
Published: BMC 2019-10-01
Series:BMC Musculoskeletal Disorders
Subjects:
Ligamentum Flavum
Hypertrophy
Histology
Spinal stenosis
Elastin
Fibrosis
Online Access:http://link.springer.com/article/10.1186/s12891-019-2825-4

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http://link.springer.com/article/10.1186/s12891-019-2825-4

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