The Cancer Drug Fraction of Metabolism Database

This study aims to create a database for quantifying the fraction of metabolism of cytochrome P450 isozymes for cancer drugs approved by the US Food and Drug Administration. A reproducible data collection protocol was developed to extract essential information, including both substrate‐depletion and...

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Bibliographic Details
Main Authors: Liyan Hua, Chien‐Wei Chiang, Wang Cong, Jin Li, Xueying Wang, Lijun Cheng, Weixing Feng, Sara K. Quinney, Lei Wang, Lang Li
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.12417