Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate

Inositols (myo-inositol and inositol hexakisphosphate) exert a wide range of critical activities in both physiological and pathological settings. Deregulated inositol metabolism has been recorded in a number of diseases, including cancer, where inositol modulates different critical pathways. Inosito...

Full description

Bibliographic Details
Main Authors:	Mariano Bizzarri, Simona Dinicola, Arturo Bevilacqua, Alessandra Cucina
Format:	Article
Language:	English
Published:	Hindawi Limited 2016-01-01
Series:	International Journal of Endocrinology
Online Access:	http://dx.doi.org/10.1155/2016/5616807

Similar Items

Myo-Inositol Safety in Pregnancy: From Preimplantation Development to Newborn Animals
by: Nilay Kuşcu, et al.
Published: (2016-01-01)

Lactic acid and thermal treatments trigger the hydrolysis of myo-inositol hexakisphosphate and modify the abundance of lower myo-inositol phosphates in barley (Hordeum vulgare L.).
by: Barbara U Metzler-Zebeli, et al.
Published: (2014-01-01)

Regulating Inositol Biosynthesis in Plants: Myo-Inositol Phosphate Synthase and Myo-Inositol Monophosphatase
by: Styer, Jean Christine
Published: (2011)

Nutritional and Acquired Deficiencies in Inositol Bioavailability. Correlations with Metabolic Disorders
by: Simona Dinicola, et al.
Published: (2017-10-01)

Inositols in Insulin Signaling and Glucose Metabolism
by: Arturo Bevilacqua, et al.
Published: (2018-01-01)

Analogues of myo-inositol and D-myo-inositol 1,4,5-triphosphate
by: Sawyer, Debbie Ann
Published: (1993)

The enzymatic activity of inositol hexakisphosphate kinase controls circulating phosphate in mammals
by: Yusuke Moritoh, et al.
Published: (2021-08-01)

Autoinhibition of Bruton's tyrosine kinase (Btk) and activation by soluble inositol hexakisphosphate
by: Qi Wang, et al.
Published: (2015-02-01)

Inositol hexakisphosphate primes syndapin I/PACSIN 1 activation in endocytosis
by: Berggren, P.-O, et al.
Published: (2022)

Phytate (Inositol Hexakisphosphate) in Soil and Phosphate Acquisition from Inositol Phosphates by Higher Plants. A Review
by: Jörg Gerke
Published: (2015-05-01)

Effects of myo-inositol plus alpha-lactalbumin in myo-inositol-resistant PCOS women
by: Mario Montanino Oliva, et al.
Published: (2018-05-01)

Complexes of myo-inositol-hexakisphosphate (InsP6) with zinc or lanthanum to enhance excretion of radioactive strontium from the body.
by: Kazuma Ogawa, et al.
Published: (2018-01-01)

Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins.
by: Martina Egerer, et al.
Published: (2010-07-01)

Importance of inositol hexakisphosphate in plant responses to pathogens and other stresses
by: Otto, Bettina
Published: (2010)

Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles.
by: Clifton L Ricana, et al.
Published: (2020-08-01)

PCOS and Inositols: Controversial Results and Necessary Clarifications. Basic Differences Between D-Chiro and Myo-Inositol
by: Giovanni Monastra, et al.
Published: (2021-04-01)

A Role for Inositol Hexakisphosphate in N-terminal Acetylation and Mitochondrial Distribution
by: Pham, Trang Thuy
Published: (2012)

2-Benzyl-myo-inositol monohydrate
by: Richard F. G. Fr&#246;hlich, et al.
Published: (2009-11-01)

Development of a homogenous high-throughput assay for inositol hexakisphosphate kinase 1 activity.
by: Michael Wormald, et al.
Published: (2017-01-01)

Influence of pH on the cytotoxic activity of inositol hexakisphosphate (IP6) in prostate cancer
by: Blandine eBetton, et al.
Published: (2011-10-01)

Metabolic studies of myo-inositol pentakisphosphates
by: Stanley, Alison Fay
Published: (1992)

The Significance of Myo-Inositol in Nutrition and Metabolism
by: Shepherd, N. D.
Published: (1974)

The Effectiveness of Myo-Inositol and D-Chiro Inositol Treatment in Type 2 Diabetes
by: Basilio Pintaudi, et al.
Published: (2016-01-01)

Study of the insulin-sensitizing effect of myo-inositol in mouse : Evaluation of the nutritional interest of a myo-inositol supplementation
by: Croze, Marine
Published: (2013)

Altered Ovarian Inositol Ratios May Account for Pathological Steroidogenesis in PCOS
by: Vittorio Unfer, et al.
Published: (2020-09-01)

Identification of myo-inositol hexakisphosphate (IP6) as a β-secretase 1 (BACE1) inhibitory molecule in rice grain extract and digest
by: Takako K. Abe, et al.
Published: (2014-01-01)

Inhibited inositol monophosphatase and decreased myo‐inositol concentration improve wasting in skeletal muscles
by: Ji‐Hyung Lee, et al.
Published: (2020-12-01)

Combined Inositol Hexakisphosphate and Inositol Supplement Consumption Improves Serum Alpha-Amylase Activity and Hematological Parameters in Streptozotocin-Induced Type 2 Diabetic Rats
by: Shadae R. Foster, et al.
Published: (2019-01-01)

Myo-Inositol in the Treatment of Teenagers Affected by PCOS
by: Lali Pkhaladze, et al.
Published: (2016-01-01)

Analysis of Quinic Acid and of myo-Inositol in Tobacco
by: Moldoveanu SC, et al.
Published: (2012-12-01)

Novel polymers based on myo-inositol orthoformate
by: Giles, M.
Published: (1998)

Functional polymers based on myo- and scyllo-inositol
by: Kim, Tae-Hyun
Published: (2001)

Improving d-glucaric acid production from myo-inositol in E. coli by increasing MIOX stability and myo-inositol transport
by: Shiue, Eric, et al.
Published: (2016)

MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia
by: Ekin Ucuncu, et al.
Published: (2020-11-01)

Inositol hexakisphosphate inhibits osteoclastogenesis on RAW 264.7 cells and human primary osteoclasts.
by: María del Mar Arriero, et al.
Published: (2012-01-01)

Malignant H1299 tumour cells preferentially internalize iron-bound inositol hexakisphosphate
by: Sabine Windhorst, et al.
Published: (2013-10-01)

Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
by: Maria Ida Amabile, et al.
Published: (2021-07-01)

Modulators and effectors of inositol hexakisphosphate activity in prostate cancer cells : from clinical prognosis to enhanced therapeutics
by: Diallo, Jean-Simon
Published: (2012)

Modulators and effectors of inositol hexakisphosphate activity in prostate cancer cells : from clinical prognosis to enhanced therapeutics
by: Diallo, Jean-Simon
Published: (2012)

Investigation of the role of dietary myo-inositol hexakisphosphate (phytate) on the relative risk of calcium oxalate kidney stone formation in black and white male South African subjects
by: Lesotho, Ntlama
Published: (2014)