DNA Repair and Signaling in Immune-Related Cancer Therapy

DNA Repair and Signaling in Immune-Related Cancer Therapy

Cancer therapy using immune checkpoint inhibitors (ICIs) is a promising clinical strategy for patients with multiple types of cancer. The expression of programmed cell death ligand-1 (PD-L1), an immune-suppressor ligand, in cancer cells is a factor that influences the efficacy of ICI therapy, partic...

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Bibliographic Details
Main Authors: Sangeeta Kakoti, Hiro Sato, Siddhartha Laskar, Takaaki Yasuhara, Atsushi Shibata
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
DNA repair
non-homologous end joining
homologous recombination
ataxia-telangiectasia-mutated
ataxia telangiectasia and Rad3-related
immune checkpoint inhibitor
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2020.00205/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2020.00205/full

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