Targeting Tumor Microenvironment by Small-Molecule Inhibitors
The tumor microenvironment (TME) is a hypoxic, acidic, and immune/inflammatory cell–enriched milieu that plays crucial roles in tumor development, growth, progression, and therapy resistance. Targeting TME is an attractive strategy for the treatment of solid tumors. Conventional cancer chemotherapie...
Main Authors: | Shangwei Zhong, Ji-Hak Jeong, Zhikang Chen, Zihua Chen, Jun-Li Luo |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2020-01-01
|
Series: | Translational Oncology |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523319304966 |
Similar Items
-
Small molecule immunomodulation: the tumor microenvironment and overcoming immune escape
by: Arsen Osipov, et al.
Published: (2019-08-01) -
Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
by: Andrea Angeli, et al.
Published: (2020-10-01) -
Hyperthermia Targeting the Tumor Microenvironment Facilitates Immune Checkpoint Inhibitors
by: Zihui Li, et al.
Published: (2020-11-01) -
Development of small molecule inhibitors/agonists targeting STING for disease
by: Kaifeng Liu, et al.
Published: (2020-12-01) -
Small-Molecule Targets in Tumor Immunotherapy
by: Hui-Fang Zhu, et al.
Published: (2018-07-01)