Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation

Indonesian Ginger (Bangle) Extract Promotes Neurogenesis of Human Neural Stem Cells through WNT Pathway Activation

Indonesian ginger (<i>Zingiber purpureum</i> Rosc.), also known as Bangle, exhibits neurotrophic effects on cultured murine cortical neurons and in the adult mouse brain, but the underlying mechanisms remain unknown. Here, using human fetal neural stem cells (hfNSCs) as a model system fo...

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Bibliographic Details
Main Authors: Kazumi Hirano, Miwa Kubo, Yoshiyasu Fukuyama, Masakazu Namihira
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
neural stem cells
human neurogenesis
<i>Zingiber purpureum</i>
Banglene
WNT signaling
histone deacetylase
Online Access:https://www.mdpi.com/1422-0067/21/13/4772

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