Altered fibrinolytic system in rat models of depression and patients with first-episode depression

Altered fibrinolytic system in rat models of depression and patients with first-episode depression

Tissue plasminogen activator (tPA) is a serine protease involved in cleavage of neurotrophic factors. In addition, tPA and neuroserpin can also directly bind to low density lipoprotein receptor-related protein 1 (LRP1), promoting neurogenesis and neurite outgrowth. Given both the cleavage and non-cl...

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Bibliographic Details
Main Authors:	Wenxiu Han, Ruili Dang, Pengfei Xu, Gongying Li, Xueyuan Zhou, Lei Chen, Yujin Guo, Mengqi Yang, Dan Chen, Pei Jiang
Format:	Article
Language:	English
Published:	Elsevier 2019-11-01
Series:	Neurobiology of Stress
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352289519300402

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